Embarking on a PhD offers many alternatives for private {and professional} growth past scientific analysis. This instalment of the Phrases of Recommendation collection goals to supply steering and tips about harnessing these sources to construct a well-rounded CV and improve your possibilities of getting employed after your PhD. We offer two views on creating your CV to optimise profession alternatives in academia and past.
The primary perspective is by Dr Zheng-Shan Chong, a post-doctoral analysiser in Singapore, and focuses on the acquisition of a variety of abilities and expertise that would open doorways to a profession exterior of academia. Past her day job, Shan manages an article collection on bioentrepreneurship and profession growth for Biotech Connection Singapore, which has allowed her to talk to a number of analysisers who’ve efficiently transitioned to non-analysis roles. Right here, she summarises the insights gained from these conversations.
That is adopted by recommendation and suggestions from Dr Sara Clohisey, a post-doctoral analysiser in Edinburgh who modified fields after her PhD, from Drosophila cell biology to human genetics and virology. Though not fairly as dramatic as leaving academia utterly, this shift prompted her to rethink her method to writing an instructional CV in order that it will attraction to an employer from a special discipline. Sara’s perspective is especially geared in the direction of careers in analysis. We hope that these distinctive views from skilled people who’ve efficiently navigated the trail from graduate pupil to working scientist will show helpful to those that are planning their subsequent strikes after finishing a PhD.
Glycolytic inhibition: an efficient technique for creating calorie restriction mimetics
Calorie restriction mimetics embody a rising analysis discipline directed towards creating therapies that mimic the anti-aging results of long-term calorie restriction with out requiring a change in consuming habits. A variety of approaches have been recognized that embrace (1) intestinal inhibitors of fats and carbohydrate metabolism; (2) inhibitors of intracellular glycolysis; (3) stimulators of the AMPK pathway; (4) sirtuin activators; (5) inhibitors of the mTOR pathway, and (6) polyamines. A number of biotech firms have been fashioned to pursue a number of of those methods.
The target of this evaluation is to explain the approaches directed towards glycolytic inhibition. This upstream technique is taken into account an efficient means to invoke a variety of anti-aging mechanisms induced by CR. Anti-cancer and anti-obesity results are essential issues in early growth efforts. Though many dozens of candidates may very well be mentioned, the compounds chosen to be reviewed are the next: 2-deoxyglucose, 3-bromopyruvate, chrysin, genistein, astragalin, resveratrol, glucosamine, mannoheptulose, and D-allulose. Some candidates have been investigated extensively with each constructive and unfavourable outcomes, whereas others are solely starting to be studied.
A complete of 20 sufferers with facial atrophic pimples scars who accepted fractional laser remedy had been recruited: 10 sufferers handled with ablative fractional CO2 laser and 10 sufferers handled with 1565nm nonablative fractional laser. Utilizing the strategy of split-face vehicle-control examine, the left half of the face was served because the remedy aspect and accepted skincare regimens, and the suitable half was management aspect accepted car. Noninvasive bioinstrumentation of pores and skin hydration index, transepidermal water loss (TEWL), and hemoglobin index (E worth) was detected within the examine. Customary digital pictures had been taken at every go to. The pores and skin tolerance and opposed impact had been additionally evaluated by topic questionnaire.
In contrast with the management aspect, the Hemoglobin index (E worth) of the remedy aspect was improved extra considerably on the seventh day (P < .05). The pores and skin hydration index of the remedy aspect was higher than that of the management aspect on the seventh and 14th day (P < .05). After remedy, the TEWL of the remedy aspect on the seventh day was statistically considerably decrease than that of the management aspect (P < .05). Within the topic self-assessment questionnaires, 63.2% thought the restore impact of β-glucan regimens was higher than that of auto. The skincare regimens had been nicely tolerated with out apparent aspect reactions.
Swiss Startup Framework: A Extremely Efficient Community Supporting the Era of Rising Biotech Companies
For over 50 years, Switzerland has been one of many main nations driving innovation in biotechnology and its industrial functions. As we speak, some 1,000 biotech firms kind a tightly knit, cross-functional community starting from analysis by to manufacturing. This community contains R&D firms, contract analysis organizations, and extremely specialised advisors and biotech traders.
Collectively, they kind an exterior innovation pool that enhances the in-house R&D capability of the massive multi-national pharma firms. A extremely efficient startup framework, strong acceleration mechanisms, and revolutionary traders allow the emergence of a steady circulation of biotech startups that revitalize the business with new applied sciences and merchandise supporting drug growth and diagnostics.
 for cell culture) Human Collagen Type I (Fibroblast, >97%, low endotoxin) for cell culture |
|
CLGN15-N-50 |
Alpha Diagnostics |
50 mg |
EUR 1448.4 |
 T-Cell Grade Porcine Type II Collagen, 0.5 mg, lyophilized |
|
2023 |
Chondrex |
0.5 mg |
EUR 195 |
|
Description: T-Cell Grade Porcine Type II Collagen |
 Cell Culture Grade Biomaterial. 1L Liquid Collagen for Research and In-Vitro Use Only. Concentation = 4mg/mL Providing 4000mg of Collagen - 1L |
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JEL1006 |
Scientific Laboratory Supplies |
1L |
EUR 11016 |
 Cell Culture Grade Biomaterial. 100mL Liquid Collagen for Research and In-Vitro Use Only. Concentation = 4mg/mL Providing 400mg of Collagen - 100ML |
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JEL1002 |
Scientific Laboratory Supplies |
100ML |
EUR 1439.42 |
 Cell Culture Grade Biomaterial. 500mL Liquid Collagen for Research and In-Vitro Use Only. Concentation = 4mg/mL Providing 2000mg of Collagen - 500ML |
|
JEL1004 |
Scientific Laboratory Supplies |
500ML |
EUR 5875.2 |
 Supreme Plant Tissue Culture Grade Agar |
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PCTA100 |
Plant Cell Technology |
500g |
EUR 144 |
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Description: A polysaccharide complex that is produced from the red alga Rhodophyceae. The extraction of agarocytes is obtained by bleaching and hot water. Supreme Plant Tissue Culture Grade Agar offers greater clarity of plant culture media. |
Supreme Plant Tissue Culture Grade Agar |
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PCTA500 |
Plant Cell Technology |
1000g |
EUR 180 |
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Description: A polysaccharide complex that is produced from the red alga Rhodophyceae. The extraction of agarocytes is obtained by bleaching and hot water. Supreme Plant Tissue Culture Grade Agar offers greater clarity of plant culture media. |
 ELISA Grade Porcine Type II Collagen, 0.5 mg/ml x 1ml |
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2013 |
Chondrex |
0.5 mg/ml x 1 ml |
EUR 201 |
|
Description: ELISA Grade Porcine Type II Collagen |
 cell culture) Human Collagen Type IV (Placenta, >purified, low endotoxin) cell culture |
|
CLGN45-N-1 |
Alpha Diagnostics |
1 mg |
EUR 634.8 |
 Immunization Grade Porcine Type IX Collagen, 5 mg, lyophilized |
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1073 |
Chondrex |
5 mg |
EUR 331 |
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Description: Immunization Grade Porcine Type IX Collagen |
 Immunization Grade Porcine Type XI Collagen, 5 mg, lyophilized |
|
1083 |
Chondrex |
5 mg |
EUR 271 |
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Description: Immunization Grade Porcine Type XI Collagen |
 Immunization Grade Porcine Type II Collagen, 10 mg, lyophilized |
|
20031 |
Chondrex |
10 mg |
EUR 234 |
|
Description: Immunization Grade Porcine Type II Collagen |
 Immunization Grade Porcine Type II Collagen, 2 mg/ml x 5ml |
|
20032 |
Chondrex |
2 mg/ml x 5 ml |
EUR 234 |
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Description: Immunization Grade Porcine Type II Collagen |
 Cell Culture Grade Water |
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25-511 |
Genesee Scientific |
6 x 500 mL/Unit |
EUR 52.91 |
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Description: Cell Culture Tested, Sterile |
Cell Culture Grade Water |
|
25-511B |
Genesee Scientific |
6 x 1000 mL |
EUR 85.86 |
|
Description: Cell Culture Tested, Sterile |
 Hepes Cell Culture Grade |
|
AK3268-0250 |
Akron Biotech |
250g |
Ask for price |
Hepes Cell Culture Grade |
|
AK3268-0500 |
Akron Biotech |
500g |
Ask for price |
Hepes Cell Culture Grade |
|
AK3268-1000 |
Akron Biotech |
1kg |
Ask for price |
 Water, Cell Culture Grade |
|
CA018-600 |
GenDepot |
6x1000ml |
EUR 148.8 |
 CELL CULTURE GRADE WATER |
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IB42010 |
IBI Scientific |
1L |
EUR 41.13 |
|
Description: DBL DIST. - 0.1 MICRON STERILE |
CELL CULTURE GRADE WATER |
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IB42011 |
IBI Scientific |
6x1L |
EUR 239.38 |
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Description: DBL DIST. - 0.1 MICRON STERILE |
CELL CULTURE GRADE WATER |
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IB42012 |
IBI Scientific |
12x1L |
EUR 469.02 |
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Description: DBL DIST. - 0.1 MICRON STERILE |
CELL CULTURE GRADE WATER |
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IB42020 |
IBI Scientific |
2L |
EUR 59.67 |
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Description: DBL DIST. - 0.1 MICRON STERILE |
CELL CULTURE GRADE WATER |
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IB42021 |
IBI Scientific |
6x2L |
EUR 342.87 |
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Description: DBL DIST. - 0.1 MICRON STERILE |
CELL CULTURE GRADE WATER |
|
IB42030 |
IBI Scientific |
10L |
EUR 194.72 |
|
Description: JUG W/HANDL 0.1 MICRON STERILE |
 Cell Culture Grade Water, Cell Culture Tested, Sterile |
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CCM1081-500 |
Bio Basic |
500 mL |
EUR 73.49 |
|
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Cell Culture Grade Water, Cell Culture Tested, Sterile |
|
CCM2081-1000 |
Bio Basic |
1000 mL |
EUR 82.64 |
|
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) Fish Serum (cell culture grade) |
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GWB-AE89C9 |
GenWay Biotech |
10 ml |
Ask for price |
 DMSO Bio-Max, Cell Culture Grade |
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40470005-1 |
Bio-WORLD |
50 mL |
EUR 107.8 |
|
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DMSO Bio-Max, Cell Culture Grade |
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40470005-2 |
Bio-WORLD |
100 mL |
EUR 182.76 |
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DMSO Bio-Max, Cell Culture Grade |
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40470005-3 |
Bio-WORLD |
25 mL |
EUR 65.65 |
|
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DMSO Bio-Max, Cell Culture Grade |
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40470005-4 |
Bio-WORLD |
250 mL |
EUR 333.31 |
|
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 Albumin, Recombinant Human - Cell Culture Grade |
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MBS172027-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
 Human Collagen I Coated Culture Ware - T25 10flasks / pack |
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cAP-5002-t25 |
Angio Proteomie |
1Pack |
EUR 198 |
 Human Collagen I Coated Culture Ware - T75 10flasks / pack |
|
cAP-5002-t75 |
Angio Proteomie |
1Pack |
EUR 316.8 |
 - Cell Culture Grade; Human Albumin) Albumin (ALB) - Cell Culture Grade; Human Albumin |
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MBS173677-100mg |
MyBiosource |
100mg |
EUR 185 |
Albumin (ALB) - Cell Culture Grade; Human Albumin |
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MBS173677-1g |
MyBiosource |
1g |
EUR 315 |
Albumin (ALB) - Cell Culture Grade; Human Albumin |
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MBS173677-5x1g |
MyBiosource |
5x1g |
EUR 1205 |
 + Heparin) ECGF (Crude Extract, cell culture grade) + Heparin |
|
300-090H |
Angio Proteomie |
6mg |
EUR 115.2 |
 Horse Serum, Heat Inactivated, Cell Culture Grade |
|
TBS8007 |
Tribioscience |
500 mL |
EUR 78 |
, (recombinant) (cell culture grade)) TNF-alpha (human), (recombinant) (cell culture grade) |
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MBS566189-001mg |
MyBiosource |
0.01mg |
EUR 305 |
TNF-alpha (human), (recombinant) (cell culture grade) |
|
MBS566189-005mg |
MyBiosource |
0.05mg |
EUR 880 |
TNF-alpha (human), (recombinant) (cell culture grade) |
|
MBS566189-5x005mg |
MyBiosource |
5x0.05mg |
EUR 3905 |
 Human Collagen I Coated Culture Ware - 12 wells 5plates/ pack |
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cAP-5002-w12 |
Angio Proteomie |
1Pack |
EUR 168.3 |
 Human Collagen I Coated Culture Ware - 24 wells 5plates/ pack |
|
cAP-5002-w24 |
Angio Proteomie |
1Pack |
EUR 178.2 |
 Human Collagen I Coated Culture Ware - 384 wells 5plates/ pack |
|
cAP-5002-w384 |
Angio Proteomie |
1Pack |
EUR 396 |
 Human Collagen I Coated Culture Ware - 48 wells 5plates/ pack |
|
cAP-5002-w48 |
Angio Proteomie |
1Pack |
EUR 198 |
 Human Collagen I Coated Culture Ware - 6 wells 5plates/ pack |
|
cAP-5002-w6 |
Angio Proteomie |
1Pack |
EUR 158.4 |
 Human Collagen I Coated Culture Ware - 96 wells 5plates/ pack |
|
cAP-5002-w96 |
Angio Proteomie |
1Pack |
EUR 247.5 |
) N-Acetyl-L-cysteine (>99%, cell culture grade) |
|
NALC15-1 |
Alpha Diagnostics |
1 g |
EUR 270 |
N-Acetyl-L-cysteine (>99%, cell culture grade) |
|
NALC15-5 |
Alpha Diagnostics |
5 g |
EUR 489.6 |
 0.05EU/mg) r-Trypsin - Type Standard ACF ex. Porcine for cell culture, 800U/mg, Endotoxin (BET) 0.05EU/mg |
|
65972 |
Sisco Laboratories |
100 Mg |
EUR 50.23 |
|
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Description: Part B1 |
r-Trypsin - Type Standard ACF ex. Porcine for cell culture, 800U/mg, Endotoxin (BET) 0.05EU/mg |
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65972-1 |
Sisco Laboratories |
1 Gms |
EUR 167.17 |
|
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Description: Part B1 |
r-Trypsin - Type Standard ACF ex. Porcine for cell culture, 800U/mg, Endotoxin (BET) 0.05EU/mg |
|
65972-2 |
Sisco Laboratories |
5 Gms |
EUR 334.34 |
|
|
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Description: Part B1 |
 ELISA Kit) Porcine Collagen Type I (Col I) ELISA Kit |
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MBS161202-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4170 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS161202-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 365 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS161202-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2115 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS161202-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 505 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS9301022-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS9301022-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS9301022-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Porcine Collagen Type I (Col I) ELISA Kit |
|
MBS9301022-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
 Porcine Collagen Type I ELISA kit |
|
E01A54455 |
BlueGene |
96T |
EUR 700 |
|
Description: ELISA |
Porcine Collagen Type I ELISA kit |
|
E07C0014-48wellsplate |
BlueGene |
48 wells plate |
EUR 280 |
Porcine Collagen Type I ELISA kit |
|
E07C0014-96wellsplate |
BlueGene |
96 wells plate |
EUR 405 |
 Porcine Collagen Type I ELISA Kit |
|
MBS725636-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Porcine Collagen Type I ELISA Kit |
|
MBS725636-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Porcine Collagen Type I ELISA Kit |
|
MBS725636-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Porcine Collagen Type I ELISA Kit |
|
MBS725636-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
 Jellagen Jellyfish Collagen Coated Cultureware 96-Well Plates. Suitable for Cell Culture Research Purposes - PK5 |
|
JEL1016 |
Scientific Laboratory Supplies |
PK5 |
EUR 229.13 |
 Jellagen Jellyfish Collagen Coated Cultureware 24-Well Plates. Suitable for Cell Culture Research Purposes - PK5 |
|
JEL1018 |
Scientific Laboratory Supplies |
PK5 |
EUR 229.13 |
 Elisa Kit) Porcine Collagen Type I (COL1) Elisa Kit |
|
EIA05501p |
Enlibio |
each |
EUR 520 |
 Elisa Kit) Porcine Collagen Type I (COL1) Elisa Kit |
|
MBS260729-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Porcine Collagen Type I (COL1) Elisa Kit |
|
MBS260729-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Porcine Collagen Type I (COL1) Elisa Kit |
|
MBS260729-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Porcine Collagen Type I (COL1) Elisa Kit |
|
MBS260729-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
ELISA Kit) Porcine Collagen Type I(COL1)ELISA Kit |
|
NSL1038Po |
Sunlong |
96T |
EUR 528 |
|
|
|
Description: Sandwich ELISA |
 Specialities) Bovine ECGF (Crude Extract, cell culture grade) Specialities |
|
300-090 |
ReliaTech |
6 mg |
EUR 31.5 |
|
Description: Endothelial cell growth factor (ECGF) is an extract of bovine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows cultivating endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
Bovine ECGF (Crude Extract, cell culture grade) Specialities |
|
300-090-5 |
ReliaTech |
5x6 mg |
EUR 147 |
|
Description: Endothelial cell growth factor (ECGF) is an extract of bovine brain containing growth promoting factors for vascular endothelial cells of mammalian origin. ECGF has also been reported to be beneficial as a media supplement for the fusion and growth of hybridoma cells in monoclonal antibody production. Endothelial cell growth factor is prepared using a modification of the method of Maciag, et al. (1979) lyophilized from a sterile solution containing NaCl and streptomycin sulfate. Endothelial cells from human umbilical vein (HUVEC) can be established as primary cultures by traditional methods. The serial propagation of these cells has proved to be difficult. The long-term propagation of these cells in vitro can be achieved with an extract prepared from bovine brain. The introduction of a fibronectin or collagen matrix to the cell culture system allows to cultivate endothelial cells at clonal densities. With ECGF, the FCS requirement can be reduced. Heparin potentiates the mitogenic activity of crude preparations of ECGF. ECGF has also been reported to eliminate the need for feeder cells in the clonal growth of hybridomas and other cell types. |
 CORNING® BIOCOAT™ COLLAGEN 150CM² RECTANGULAR CANTED NECK CELL CULTURE FLASK WITH VENTED CAP |
|
356486 |
CORNING |
5/pk |
EUR 585.6 |
|
Description: Advanced Cells - DL; Flasks BCT |
Switzerland Innovation, the Swiss innovation park with its 5 branches, is facilitating collaborations for firms, startups, and universities to search out options to a number of the world’s most urgent challenges within the fields of well being and the life sciences, specifically within the areas of chemistry, biochemistry, biomedicine, biotech, medtech and digital well being. Along with its quite a few and various companions, Switzerland Innovation creates an ecosystem for universities and analysis-based firms, accelerating the transformation of analysis outcomes into marketable services and products.
